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The identification of neuroprotective agents for PD provides us with therapeutic opportunities for modifying the course of disease progression and, perhaps, reducing the risk of onset when preclinical biomarkers become available
Although the feasibility of measuring GSH with MRS has already been demonstrated [25], it is still difficult to translate this procedure into clinical practice because of the low GSH concentration in the brain (1.53 mmol/L), low signal-to-noise ratio (SNR) of the brain spectra, and severe spectral overlapping between metabolites with different peak intensities [23]
Highly sensitive curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of alzheimer's disease via NLRP3-inhibition
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AMPylation matches BiP activity to client protein load in the endoplasmic reticulum
The best glutathione supplement works at this cellular level, helping support collagen preservation and antioxidant defense before the signs deepen
