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(2017) demonstrated that IL-1 induces phosphorylation of p38 MAPK, upregulates MLCK expression, and enhances paracellular permeability in the intestinal epithelial cells

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Taken together, TMQ0153 shows promise as a combination therapy to restore drug sensitivity in TP53-mutated AML via metabolic interference

This was followed by successive incubations with anti-5-mC primary antibody, HRP-labeled secondary antibody, and chemiluminescent substrate

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Abib FC, Schaefer ARC, Schaefer TMC, Godois R, Laing RA