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However, IGF1 has no significant impact on muscle mitochondrial function, indicating that the deficiency of IGF1 in male mice has different roles on tissue mitochondrial function between the center and periphery circulation (Pharaoh et al., 2020)

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Satellite Cell Activation and Muscle Regeneration Growth hormone secretagogues such as MK-677, CJC-1295, and Ipamorelin enhance the GH/IGF-1 axis, increasing satellite cell proliferation and promoting new muscle fiber repair