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Platelets, when activated, form aggregates with erythrocytes, monocytes, and neutrophils both in patients and in murine models (Wun et al., 1997

41 Constitutional manifestations such as fatigue, depression, nausea, pain and loss of appetite are common in patients with cancer, and it was shown that intravenous administration of vitamin C reduces these complications and has palliative applications

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There was an overall weight gain in these patients and a decrease in the frequency of clinical signs such as vomiting and diarrhea

doi: 10.1016/j.envint.2004.10.001

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