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N-acetylcysteine, SARS-CoV-2, and male reproduction N-acetylcysteine (NAC) has been proposed as a potential treatment, preventive and/or adjuvant against SARS-CoV-2 as it is having two major activities: first, due to presence of its free sulfhydryl group, NAC reduces the sulfide bonds in the cross-linked glycoprotein matrix in mucus thus reduced mucus viscosity and showing a mucolytic property [20, 21]

N-acetylcysteine is a precursor of L-cysteine, which in turn is a component of the endogenous antioxidant glutathione, a tripeptide composed of glutamate, cysteine, and glycine

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Notably, similar observations were reported in human studies

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