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EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines ( Where relevant data were missing, attempts were made to contact corresponding authors

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These symptoms develop gradually because the body stores several years worth of B12 in the liver, meaning deficiency takes time to become clinically apparent