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Acknowledgments The publication is supported in part by a Grant-in-Aid for Intractable Diseases from the Ministry of health, Labour and Welfare of Japan and from the Ministry of Education, Culture, Sports, Science and Technology of Japan

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The University of Colorado Animal Imaging Shared Resources are supported by the University of Colorado Cancer Center (NCI P30 CA046934) and the Colorado Clinical and Translational Sciences Institute (NIH/NCATS UL1 TR001082)