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(85) demonstrated that ADA-409-052as an effective ferroptotic inhibitorcan reduce lipid peroxidation, GSH depletion, and GPX4 inactivation, inhibit the pro-inflammatory activation of BV2 microglia, protect N2a neurons from inflammatory macrophage damage, down-regulate the expression of pro-inflammatory genes, shrink infarct volume, and mitigate edema in mouse models of stroke

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Then all animals were randomly divided into five groups (n=10) as follows: group I (model control) rats were administrated plain hydrogel alone

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In brief, MSCs were re-plated at a clonal density of 60 cells/well in six-well culture plates and cultured in hES-MSC medium for 14 days