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C.GabbardJ.GallandK.Aceves-AvilaM.HolbertK

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HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice

Oxidative stress and intracellular pathway Origin of hepatic fibrosis is initiated by the damage of hepatocytes, resulting in the recruitment of inflammatory cells and platelets, and activation of kupffer cells, with subsequent release of cytokines and growth factors

Therefore, the simultaneous targeting of OXPHOS and glycolysis represents a promising strategy for antitumor bioenergetic therapy through synergistic mechanisms [154]