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Reviewer 2 This is a straightforward paper that addresses whether tamoxifen affects neurogenesis and whether there is any difference if it is given IP or orally

Long-term safety considerations favor peptides with decades of topical use showing no concerning patterns, while Botox long-term effects remain incompletely understood with questions about muscle atrophy from chronic paralysis, antibody formation reducing effectiveness requiring dose escalation, and potential spreading effects from repeated treatments though definitive evidence proving harm remains limited

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Abstract There has been little success in controlling Johnes disease, caused by Mycobacterium avium subsp

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