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Pyridoxine can serve as a buffer, allowing faster dose escalation while keeping nausea within tolerable limits

In addition to genetic regulators, intracellular iron accumulation, excessive lipid peroxidation, and small molecules can also trigger ferroptosis [6, 17]

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Hur E.-M., Zhou F.-Q

Oxidized arachidonic/adrenic phosphatidylethanolamines navigate cells to ferroptosis

[DOI] [PubMed] [Google Scholar] 33.Vukojevic J, et al

Specifically, they can inhibit T cell proliferation and antitumor immune response through cysteine, arginine, and tryptophan deprivation, ROS release, and PD-L1 expression
