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Tenovin-1 is a potent and selective SIRT1 and SIRT2 inhibitor, which can significantly inhibit the enlargement and vacuolation of proximal and distal tubes, thickening of GBM, and lipid droplet accumulation in the HFD-induced DKD rat model and NRK-52E cells treated with HG

doi: 10.1038/s41598-019-45171-6 104 BallardPLBallardRA

C., Parkinson-Like Syndrome Induced by Continuous MPTP Infusion: Convergent Roles of the Ubiquitin-Proteasome System and Alpha-Synuclein, Proc

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Common SLC7A11 inhibitors including sulfasalazine, erastin, sorafenib, and IKE, have shown good antitumor effects in various cancer models (Bhutia et al., 2015

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