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Noom is the latest digital health company to jump into the off-label weight loss drug market to make medications more accessible to consumers

Expected 12-month results include 15 to 20% body weight loss (65 to 100+ pounds for a 400-pound person), 6 to 10 inch waist circumference reduction, transformative improvement in daily functional capacity, and resolution or significant improvement of multiple obesity-related conditions

Weghuber, D., Barrett, T., Barrientos-Prez, M., Gies, I., Hesse, D., Jeppesen, O

10.1038/ajg.2013.7 87 SoaresH

Long interested in Holst's work, in 1990 Novo Nordisk recruited his colleague Schwartz to develop small molecules able to activate the GLP receptor in the pancreas (Molteni, Chen)
