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The role of istradefylline in the Parkinsons disease armamentarium

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Methotrexate, used in chemotherapy and autoimmune disease, blocks folate metabolism directly, and the seizure drug phenytoin lowers folate too

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10.1186/2045-8118-10-2 Fluids Barriers CNS 45 LiuW

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The results revealed increased lipid peroxidation levels, progressive damage, and cell death in the hippocampus

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Plus heart protection, muscle support, and reduced zombie cell accumulation

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