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This work established the broader significance of NNMT in methylation-dependent cellular processes and provided context for the development of selective inhibitors [3]

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In studies where beta-3 receptors were genetically deleted, the peptide lost its fat-reducing effects, confirming this pathways critical role

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In addition, amino acids also serve as precursors of many important metabolites that regulate gene expression, post-translational modifications of proteins, cell fate, etc