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Further pharmacological investigations and clinical trials are warranted to validate their efficacy as monotherapy or adjunctive treatments in pediatric neuropsychiatric disorders, particularly in patients sensitive to adverse drug reactions or requiring long-term management

Its multi-targeted actions in models of PD, AD, and other neurodegenerative disorders highlight curcumins potential as a neuroprotective nutraceutical

1.1 Glutathione peroxidase Glutathione peroxidase (GPx) an mammalian enzyme, contains selenocysteine residue in its active site, For the last four decades, an extensive research has been carried out on the mammalian antioxidant enzymes GPx [34]

Within this broad category of diffuse lung diseases, IPF belongs to the subgroup known as idiopathic interstitial pneumonia (IIP)

Open questions What are the therapeutic targets or strategies suitable for the various diabetic complications

In conclusion, it is revealed that curcumin is effective for activation and restoration of p53 levels especially in the cells with an abnormal p53 expression or function