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(2023) 325:H6734

LNK is mainly expressed in hematopoietic cells and is known to be important for regulating a number of signaling pathways mediated by the TPOR (MPL), erythropoietin receptor (EPOR), stem cell factor receptor (KIT and SCFR), macrophage colony-stimulating factor receptor (CSF1R and C-FMS), and platelet-derived growth factor receptor (PDGFRB)

doi: 10.1097/MNH.0000000000000381

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2 Pathophysiological foundations of chemotherapy-induced neurotoxicity The development of CIPN involves multiple convergent mechanisms that fundamentally alter the neurobiological landscape of peripheral nervous system function