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Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-B/MAPK pathways via binding to TAK1

Salerno S, Granata C, Trapenese M, Cannata V, Curione D, Rossi Espagnet MC, Magistrelli A, Tom P

To a large extent, p53 maintains genomic stability by causing death or growth arrest in damaged cells

Transferring the immunoglobulin G (IgG) portion of blood from fibromyalgia patients to mice dramatically reduces the animals pain threshold

It has been demonstrated to improve brain function and short-term memory in healthy older adults

A study from 2013 cites this mechanism as the reason the chemotherapy drug irinotecan was increased in the colonic lining of rats pretreated with curcumin, a result that points to possibly enhanced therapeutic benefit in the treatment of colon cancer, although the potential of increasing cytotoxic side effects was not studied