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Preventive effects and mechanisms of garlic on dyslipidemia and gut microbiome dysbiosis
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UPR is a highly conserved pathway that monitors endoplasmic reticulum (ER) proteostasis, allowing cells to manage ER stress (Moncan et al., 2021)

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In colonic epithelial cells, TMAO induces NF-B-dependent upregulation of IL-8 and TNF-, disrupting tight junctions and increasing permeability (102, 103)
