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Additionally, whether the mechanism by which metformin reduces hepatic gluconeogenesis through mitochondrial ETC inhibition is related to iron metabolism requires further validation

[PubMed] [Wiley] Li Y, He B, Li H, Zhang Q, Tang C, Du J, Jin H

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Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury

Blood and lymphatic system disorders: anemia Gastrointestinal disorders: diarrhea General disorders and administration site conditions: pyrexia, injection site pain Metabolism and nutrition disorders: hypokalemia, hypomagnesemia, hypoalbuminemia, hypophosphatemia Musculoskeletal and connective tissue disorders: muscle spasm Nervous system disorders: headache Psychiatric disorders: agitation Renal and urinary disorders: oliguria Respiratory, thoracic and mediastinal disorders: atelectasis, pleural effusion, pulmonary edema, stridor, wheezing Vascular disorders: hypotension, hypertension 7.1 Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential