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Closer examination revealed 211 DEGs when comparing the GR mutant strain to the WT strain, with 123 genes upregulated and 88 genes downregulated in the GR mutant strain (Figure 3B)

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There are four broad mechanisms that have been identified for inducing ferroptosis(1) inhibition of system x c , (2) inhibition/degradation/inactivation of GPX4, (3) depletion of reduced CoQ 10 , and (4) induction of lipid peroxidation through peroxides, iron, or PUFA overload

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DCs play a vital role in activating adaptive immunity as professional antigen-presenting cells

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In some instances, the therapeutic AuNPs have also been designed to have molecules that facilitate active targeting of the AuNPs toward specific cells and tissues

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10.1111/bph.12875 57 XieY.HouW.SongX.YuY.HuangJ.SunX.et al (2016)

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