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Policy Lipedema is a long-term condition that causes abnormal fat buildup in the lower part of your body

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Being teratogenic in nature it is contraindicated in pregnant women (Yao et al., 2020

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Starting at 0.5mg instead of 1mg allows MC4R receptors to downregulate gradually, reducing symptom intensity

P Natl Acad Sci USA (2012) 109:55238