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doi: 10.1172/jci.insight.90133 43 OlaV.PuriI.GoswamiD.VibhaD.ShuklaG.GoyalV.et al

Spectral domainoptical coherence tomography (SD-OCT) scans through the fovea are shown for a patient with moderately severe loss of EZ width ( A , margins marked by blue lines) and severe loss of EZ width ( B )

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Preclinical Studies in Ototoxicity Models A study carried out both in cultured cells and in an animal model (male and female mice) demonstrated the strong beneficial potential of ALA in rescuing ototoxic hearing loss caused by cisplatin