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The absorption is very efficient in the distal ileum (enterohepatic recirculation)

Bioavailability: 1 to 2% absorbed passively without intrinsic factor Deficiency: only if GI absorption is intact Dosing: daily, high-dose oral Prescription: no, available OTC At home: yes Get a B12 injection prescription Not sure which format fits your situation

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But you know, at this point, it's kind of off the table

Account for this by adding 0.1-0.2 mL extra bacteriostatic water during reconstitution, or simply accept that the last draw from a vial may be slightly less than intended