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The activity of folylpolyglutamate synthase is lowest towards 5-methyl-THF and this prevents this form of the vitamin from being trapped within intestinal enterocytes

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Increased intramitochondrial concentrations of ADP cause the PMF to become discharged as protons pour through ATP synthase, regenerating the ATP pool

Beyond those roles, lncRNAs contain small open reading frames (smORFs), which code for microproteins that may fulfill a functional role in MSC biology as post-translational modifiers