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The most promising candidates are pharmacologically innovative next generation TrkB agonists (ANA-12 derivatives) that reproduce BDNF activity and circumvent secretion deficits

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These are not dietary supplements, they are not approved drugs, they are chemicals with no good manufacturing practices (GMP) or quality control testing requirements for identity or contaminants as is required for supplements

Sivamani 2010)

Knowing the total quantity helps researchers plan and scale their experiments accurately