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Taken together, in contrast to obese mice, infiltration of immune cells is not enhanced in Cpt1b m/ muscle despite excess amounts of metabolic stimuli such as FA
Consumption of a high fat diet results in a surplus of NADH and FADH 2 that then increases the flux through the ETC with a resultant increase in ROS generation
(2024) confirmed dose-dependent body-weight and fat-mass reduction over a longer treatment window, with improvements in fatty-liver markers
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