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Various pro-inflammatory cytokines were significantly increased in the UVB irradiation group compared with those in the non-irradiated group

doi: 10.1056/NEJM199401133300208

doi: 10.1182/blood-2006-04-016451 30 CaoXCaiSFFehnigerTASongJCollinsLIPiwnica-WormsDRet al

Brain fog: High histamine levels can be a cause of brain fog or cognitive issues Canker sores, oral lesions, or burning mouth.[ref] Periodic Limb Movement Disorder: Animal studies show that H3 receptor activation causes limb movements during sleep Autoinflammatory conditions, such as familial Mediterranean fever: People with FMF have higher-than-normal histamine levels during a flare-up

The results of several ongoing combination trials with various agents are eagerly awaited