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Third, although pharmacological modulators of ferroptosis have shown promise in preclinical models, their translational relevance remains uncertain, and the lack of an integrated mechanistic framework hampers rational therapeutic development

However, recent studies have found that moderate supplementation of lactate after ischemic injury and reperfusion is more effective than glucose in improving neurological outcomes [101]

[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Jiang Y, Li G, Liu J, Li M, Li Q, Tang K

Knockdown of Chac2 (Sh-Chac2) via lentiviral transduction significantly reduced its expression at both the mRNA and protein levels, as confirmed by RT-qPCR and Western blot (Fig

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Chepikova OE, Malin D, Strekalova E, Lukasheva EV, Zamyatnin AA Jr, Cryns VL
