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While we are still a long way away from pinpointing an analogous pathogenic species in MS, once identified, a specific immunotherapy targeting the relevant misfolded proteins, rather than downstream immune effectors as is the current approach, could be more effective in the progressive stages of MS

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Systematic review, meta-analysis and guideline]

Wang, L., et al

By synthesizing a molecule that could permeate the cell membrane and selectively inhibit NNMT, researchers discovered they could fundamentally alter the metabolic profile of the cell

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