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albicans infection leads to a significant reduction in mucosal bacterial diversity, accompanied by the abnormal overgrowth of Enterococcus on oral and small intestinal mucosae, and the overproliferated Enterococcus can degrade the epithelial junction protein E-cadherin in vitro and in vivo , destroy the integrity of the mucosal epithelial barrier and increase its permeability

showed that human hUC-MSCs transduced with fibroblast growth factor-20 (FGF-20) via adenoviral vectors increased the expression of TH and DA levels in the substantia nigra of the PD mouse model, leading to an improvement in motor behavior [91]

Glutathione is also recognized as a thiol buffer maintaining sulfhydryl groups of many proteins in their reduced form

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Such important mechanisms, nonetheless, fail to fully account for the in vitro and in vivo immunologic actions of DMF (39)