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At least two studies suggest that SFs neuroprotection may stem from decreased BBB permeability, improved cell survival, and/or enhanced aquaporin-4 (AQP4) channel presence
The downregulation of Nrf2 is implicated in fostering oxidative stress in AD pathology [156]
This strategy integrates the dual roles of ammonia into a novel paradigm of spatiotemporal regulationmetabolic interventionimmune synergy, offering a new approach to overcome the limitations of CAR-T therapy
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