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Description
Hepatotoxicity would be shown to be a consequence of CYP-mediated metabolism to NAPQI and differences in this metabolic pathway are a key determinant of relative sensitivity to its hepatotoxicity
Poly(ADP-ribose) drives pathologic -synuclein neurodegeneration in parkinson's disease
This includes: Direct evidence: directly measured experimental support that blocking or preventing a KE prevents or impacts downstream KEs in the pathway in the expected fashion
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10.1111/j.1365-2605.2008.00951.x 244
A) controls distilled water (without any antioxidants)
Lu YY, Wu CH, Hong CH, Chang KL, Lee CH
