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Neuropsychiatr Dis Treat 15:1429 Kanthan R, Shuaib A, Griebel R, El-Alazounni H, Miyashita H, Kalra J (1996) Evaluation of monoaminergic neurotransmitters in the acute focal ischemic human brain model by intracerebral in vivo microdialysis

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It was shown that treatment with dried powdered ginger rhizome improved both allodynia and hyperalgesia by decreasing the inflammatory responses mediated by nitric oxide (NO), prostaglandin E2 (PGE2), thromboxane B2 (TXB2), and interleukin-1 (IL-1) in lipopolysaccharide (LPS)-stimulated macrophages in FMS model mice, indicating that macrophages may contribute to NPP through the release of pro-inflammatory mediators (56)

It was developed as a pharmaceutical drug and one small clinical trial was filed but it was canceled

The problem is that it breaks down in the stomach, and does not make it intact to the cells where it is needed

Journal of Biology and Today's World
