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Other platinum-based drugs, such as oxaliplatin and carboplatin, exhibit varying degrees of ototoxicity, with carboplatin being more selective for inner hair cells, while oxaliplatin has a comparatively lower ototoxic potential

Antioxidant support is often a "quiet" benefit that builds over time

Administration of NRF2 activator, which would be favorable for reinvigorating anti-tumor immunity and conferring the metabolic liabilities on cancer cells, in combination with inhibitors of glutamate and/or NEAA synthesis may be an effective anti-tumor therapy from the viewpoint of interaction between cancer cells and their microenvironment

10.1080/02699052.2019.1566968 Brain Inj

Chloramines, which are generally weaker oxidants than HOCl, are generated by the action of HOCl upon biological amines

Although small-molecule drugs such as metformin and cisplatin are frequently used as pyroptotic inducers, they suffer from rapid clearance, non-specific distribution and systemic side effects