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He is recommending that others switch to compounded semaglutide, which is what roughly 75% of Chronos patients are taking, he said

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Site Rotation: Rotate systematically between injection sites (abdomen at least 2 inches from navel, outer thighs, upper arms, upper buttocks) to prevent lipohypertrophy and local irritation [14]

A responsible plan may include adequate protein intake, resistance training, walking or other appropriate activity, body composition tracking when available, lab monitoring, gradual dose escalation when appropriate, nutrition support during appetite reduction, hydration and electrolyte guidance, monitoring fatigue or excessive appetite suppression, and evaluation for hormone, thyroid, or nutrient issues when relevant