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Because they act on separate receptors (GHRH receptor vs GHS-R), combining them lets researchers study combined upstream GH-axis stimulation rather than a single pathway in isolation

Schiff et al., 2003)

Hydrolysis of cysteinylglycine and of cysteinylglycine S -conjugates formed from the -glutamyl transpeptidase-mediated degradation of GSH and GS-conjugates, respectively, is mediated by various dipeptidase activities, including the plasma membrane-bound ectoenzyme aminopeptidase N (Figure 1C), and cytosolic leucyl aminopeptidase (EC 3.4.11.1

doi: 10.1038/s41514-025-00237-w.Google Scholar Cheah, IK, Lee, JZ, Tang, RMY et al

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Physiology does not reward extremesit adapts to them