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Type II DGK, which includes the delta, eta, and kappa isoforms, each contain an N-terminal pleckstrin homology (PH) domain that interacts with phosphatidylinositol, a C-terminal sterile -motif (SAM) domain, and two catalytic domains in addition to the two C1 domains

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doi:10.1016/j.jaad.2005.11.1061