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This study provided evidence that ketogenic diets may be feasible, effective, and safe in the long-term in adults, although long-term adherence was limited

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Do not exceed the recommended dose unless advised by a healthcare professional

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Paradoxically, while normal prostate physiology prioritizes polyamine synthesis (e.g., spermine), regulated by androgen-dependent enzymes like ODC to support secretory functions, PCa progression exhibits a contradictory polyamine landscape: spermine levels decline sharply despite ODC overexpression, a phenomenon contrasting with polyamine accumulation patterns in other cancers

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While GGT5 and GGT1 share 40% of the amino acid sequence (22), GGT5 is not as active in hydrolyzing GSH, GSSG and leukotriene C4 as GGT1 is (29)

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Its broad benefitsranging from bone strength and immune resilience to mood balance and hormonal regulationmake it one of the most valuable therapies in preventive and functional medicine

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Nov 2021 Frontiers Media S A Peng, C., Chen, Y., & Jiang, M

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