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This study provided evidence that ketogenic diets may be feasible, effective, and safe in the long-term in adults, although long-term adherence was limited

Do not exceed the recommended dose unless advised by a healthcare professional

Paradoxically, while normal prostate physiology prioritizes polyamine synthesis (e.g., spermine), regulated by androgen-dependent enzymes like ODC to support secretory functions, PCa progression exhibits a contradictory polyamine landscape: spermine levels decline sharply despite ODC overexpression, a phenomenon contrasting with polyamine accumulation patterns in other cancers

While GGT5 and GGT1 share 40% of the amino acid sequence (22), GGT5 is not as active in hydrolyzing GSH, GSSG and leukotriene C4 as GGT1 is (29)

Its broad benefitsranging from bone strength and immune resilience to mood balance and hormonal regulationmake it one of the most valuable therapies in preventive and functional medicine

Nov 2021 Frontiers Media S A Peng, C., Chen, Y., & Jiang, M
