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Currently available GLP-1 receptor agonists in the United States include exenatide (Byetta, Bydureon BCise), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), semaglutide (Ozempic, Wegovy, Rybelsus), and tirzepatide (Mounjaro, Zepbound), though tirzepatide is technically a dual GIP/GLP-1 receptor agonist

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Semaglutide mimics glucagon-like peptide-1, a hormone regulating blood sugar and satiety

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Participants on the 5mg dose lost an average of 16.0% of their body weight