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Discussion Solar radiation is one of the important external factors in skin pathogenesis that can lead to many complications

Research links environmental exposure to TAO, where pollutants induce ROS through oxidation reactions, increasing intracellular oxidative stress (78, 79)

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Cuenca RE, Allison RR, Sibata C, Downie GH

Notably, miR-4443 has been implicated in tumorigenesis, metastasis, and chemotherapy resistance, underscoring its dual role in cancer progression [103]
