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If you have an older senior horse , look out for the following signs of poor joint health and consider adding MSM to the diet: Puffiness around a joint, particularly the hocks Warmth or pain in a joint Changes in how the horse moves

However, the impact of supplementation on bone tissue appeared to be limited and varied according to the season

doi: 10.1073/pnas.94.12.6474 59

The relationship between BPC-157 and cancer remains unclear

In mice, a genomic approach combined with cytokine measurements has shown that a low Se diet led to increased activity of IFN- and IL-6 pathways as well as IL-6 levels (Reference Tsuji, Carlson and Anderson69)