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When ALD advances to cirrhosis, liver failure, or hepatocellular carcinoma, where the liver loses normal function and conventional treatments are ineffective, liver transplantation becomes the most effective method to increase survival rates by providing a normally functioning liver

As such, phototoxicity is likely more prevalent than reported in the literature

Taken together, these results show that MRP7 is an endogenous resistance factor for taxanes, vinca alkaloid anticancer drugs, and nucleoside analogs[168]

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699 Homoharringtonine-based regimen is also beneficial to childhood AML

High performance liquid chromatography and mass spectrometry Synthetic GS-MQ or APR-246 treated de-proteinized JH-EsoAd1 cell lysates were resolved on an ODS-Hypersil C18 HPLC column (2.1 100 mm, 5 m, Hewlett-Packard) in 10 mM NH 4 HCO 3 pH 8, using a 080% acetonitrile gradient over 10 min