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This modification crosstalks with the adjacent arginine 3 asymmetric dimethylation mark (H4R3me2a) to regulate ribosomal RNA expression in response to glucose levels suggesting that Nat4 and NacH4 act as a sensor for cell growth (Schiza et al., 2013)

Pignolo et al

Rh2 impedes proliferation and migration and stimulates apoptosis of osteosarcoma cells [18]

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