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These models also enable the analysis of tumour-subtype specificity, interplay with chemotherapeutic or targeted compounds and potential organ-specific toxicities such as hepatic-, nephro- and cardiovascular-toxicity

The exhaustion of T E and T M cells does not follow a stepwise process

Dou H, Qin Y, Chen G, Zhao Y

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor -independent mouse model

Safety, tolerability, and anti-fibrotic efficacy of the CBP/-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: an investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study

Individual cycles individually are important, but you put them all together and it can be massive