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Furthermore, some newer agents for metastatic hormone-sensitive PCa may require more extensive preclinical testing in multiple models and need to demonstrate better synergistic effects with standard-of-care agents before introduction into clinical trials

10.1016/0005-2744(80)90004-2 [DOI] [PubMed] [Google Scholar] Lahti P

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PARP2 deficiency also enhances SIRT1 activity, however unlike PARP1, this occurs independent of NAD + level (64)

This compound has been studied extensively for its unique biochemical properties and its role in cellular pathways

Evaluation of cytotoxic effects of fungal origin nanosilver particles on oral cancer cell lines: an in vitro study