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Zebrafish xenograft model for studying mechanism and treatment of non-small cell lung cancer brain metastasis

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& Roach, J.C

The peroxynitrite-mediated activation of ERK committed bronchial (922) and neural cells (645, 1099, 1420) to apoptotic cell death, while activation of JNK, p38, or both triggered a similar outcome in murine alveolar cells (1162), cerebrocortical neurons (120), and PC12 cells (1148), respectively

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The biological effects of kinins are mediated by stimulation of constitutively expressed B2 receptors and inducible B1 receptors