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Taken together, the combined burden of on-target toxicity and off-target effects constrains the therapeutic window and constitutes a practical barrier to clinical development, making it essential to pair analog optimization with delivery strategies that confine exposure to lesions and minimize unintended pathway engagement in normal tissues

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Anti-allergic rhinitis effects of medicinal plants and their bioactive metabolites via suppression of the immune system: a mechanistic review

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What can I expect during a vitamin B12 injection appointment

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In the future, the combination of these drugs with other treatments could be explored

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Microvascular and macrovascular complications of diabetes

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Science (2014) 343:12603

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