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In Phase 1 detoxification, liver enzymes (primarily the cytochrome P450 family) process these toxins, often making them even more reactive and dangerous in the short term

[DOI] [PubMed] [Google Scholar] 109.Xu Q., Zhang L., Liu Y., Cai L., Zhou L., Jiang H., Chen J

Shahar O, Botvinnik A, Shwartz A, Lerer E, Golding P, Buko A et al (2024) Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain

344 Similarly, PEITC, a cruciferous phytochemical, selectively kills cancer cells by targeting GSH (along with ETC-III and the UPR) to induce ROS-mediated cell death, 345 with its synthetic analog LBL21 targeting stem-like cancer cells in NSCLC

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