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662 In various neurodegenerative disease models, this approach reduces misfolded protein aggregates, including pathological tau species

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PMID: 39013986 Dyes Pigm2025 Sep 16;245:113243

280 Furthermore, activation of the inflammation-related NLRP3 inflammasome signaling pathway in different types of neural cells was closely associated with high cholesterol load, which triggered neuroprotective properties in activated microglia but promoted oxidative stress in neurons, further enhancing the expression of NLRP3 inflammasomes, inducing neuronal pyroptosis, and impairing the phagocytic capacity of microglia